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9700 · 5.2

Chromosome behaviour in mitosis

Cambridge 9700 Paper 2 — Chromosome behaviour in mitosis (5.2). A-Level Notes diagram-backed lesson with premium structure and live visuals.

Need to know

What you need to know

  • Mitosis produces two genetically identical diploid (2n) daughter cells.
  • The four stages are Prophase, Metaphase, Anaphase, and Telophase (PMAT).
  • DNA replication occurs during the S phase of Interphase, creating sister chromatids.
  • Spindle fibres, made of microtubules, are essential for separating chromosomes.
  • Cytokinesis in animal cells involves a cleavage furrow; in plant cells, a cell plate forms.
  • Mitosis is vital for growth, tissue repair, and asexual reproduction.
  • The cell cycle is regulated by cyclins and CDKs at specific checkpoints.
  • Loss of cell cycle control due to genetic mutations can lead to cancer.

Explanation

Chromosome behaviour in mitosis

  1. Mitosis produces two genetically identical diploid (2n) daughter cells.
  2. The four stages are Prophase, Metaphase, Anaphase, and Telophase (PMAT).
  3. DNA replication occurs during the S phase of Interphase, creating sister chromatids.
  4. Spindle fibres, made of microtubules, are essential for separating chromosomes.