9990 · 1.1.2
Explanations of schizophrenia
9990 Clinical — biological, psychological, and sociocultural explanations of schizophrenia.
Need to know
What you need to know
- Genetic vulnerability is shown by higher concordance rates in genetically similar individuals (e.g., MZ vs DZ twins).
- Schizophrenia is considered polygenic, meaning multiple genes contribute to the risk.
- Neural correlates are observable differences in the brain, such as enlarged ventricles and reduced grey matter.
- Reduced activity in the ventral striatum is linked to avolition (a negative symptom).
Explanation
Explanations of schizophrenia
- Genetic vulnerability is shown by higher concordance rates in genetically similar individuals (e.g., MZ vs DZ twins).
- Schizophrenia is considered polygenic, meaning multiple genes contribute to the risk.
- Neural correlates are observable differences in the brain, such as enlarged ventricles and reduced grey matter.
- Reduced activity in the ventral striatum is linked to avolition (a negative symptom).