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9990 · 1.1.3

Treatment and management of schizophrenia

9990 Clinical — antipsychotics, CBT, family therapy, and community care for schizophrenia.

Need to know

What you need to know

  • Primary biological treatment, based on the dopamine hypothesis.
  • Typical antipsychotics (e.g., Chlorpromazine) block D2 receptors, mainly treating positive symptoms.
  • Atypical antipsychotics (e.g., Clozapine) act on dopamine and serotonin, treating positive and negative symptoms.
  • Significant side effects (e.g., tardive dyskinesia, weight gain) can lead to non-adherence.

Explanation

Treatment and management of schizophrenia

  1. Primary biological treatment, based on the dopamine hypothesis.
  2. Typical antipsychotics (e.g., Chlorpromazine) block D2 receptors, mainly treating positive symptoms.
  3. Atypical antipsychotics (e.g., Clozapine) act on dopamine and serotonin, treating positive and negative symptoms.
  4. Significant side effects (e.g., tardive dyskinesia, weight gain) can lead to non-adherence.